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Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor
Conditions that disrupt intestinal neuromuscular signaling can cause secondary constipation (eg, multiple sclerosis, Parkinsons disease, spinal cord injury, diabetic neuropathy, and stroke) (Basilisco 2013
From other trials, there are health benefits in a reduction of weight-related comorbidities when individuals lose 5-10% of body weight, so it is very likely their health improved
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